Jessy has been living with a disabling mystery illness that has turned his life upside down. He experiences extreme fatigue, brain fog, tremors and intense pain. His body has become so unreliable that he requires a wheelchair to navigate the world. And yet, his doctors have no idea what is Read more…
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This week we kick off the third season of Major Pain by catching up with previous guests! First we’ll check in with Andrew, who originally appeared in December 2021 to discuss mild traumatic brain injury (MTBI). He has been slowly improving since then, feeling as if a new self is Read more…
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Andi and Jesse wrap up season 2 of Major Pain by sharing their health updates and reflecting on the past year of the show. Jesse discusses his potential diagnoses of mast cell activation syndrome and small fiber neuropathy, while Andi tells us about her vocal surgery recovery.
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As a child, Alexis Kline hoped to one day be a professional soccer player. That all changed at 12 years old during soccer tryouts when Alexis started feeling so weak and sore that she needed to visit the doctor. Her soccer dreams were dashed when she was diagnosed with dysautonomia, Read more…
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Andi and Jesse share updates from their recent travels to New York and Florida, plus both of their health situations including Andi’s vocal injury and Jesse’s continued quest for a diagnosis. Jesse has seen significant improvements in his mobility, while being evaluated for mast cell activation syndrome (MCAS) and small Read more…
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Kevin has been on a diagnostic roller coaster over the past few years. He was working in a management position at a museum when he started having trouble walking, difficulty straightening up and intense pain in his feet. He also developed uveitis in his eyes, a painful inflammatory condition that Read more…
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Claudia Alick is an activist and influencer with a transmedia social justice practice, creating spaces for entertainment, education and empowerment by and for marginalized communities. While working as a disability advocate in 2009, Claudia found themself suddenly experiencing what they describe as mysterious level 10 pain, accompanied by mobility issues Read more…
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Andi and Jesse are back from their month of traveling, but things didn’t quite go as planned. They share stories from their trip to Maine for a wedding, followed by Tahoe where Andi unfortunately came down with covid. Andi shares her frustration with a series of difficult events in her Read more…
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When Ashley scheduled an interview for the Major Pain podcast to discuss her chronic illness, she was prepared to talk about living with an undiagnosed disease. But to her shock, just weeks before recording her interview, a rheumatologist officially confirmed a diagnosis. Ashley found herself looking back on her life Read more…
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Kristin has lived with pain since she was 9 years old, a journey that has taken her through chronic migraines, celiac disease, covid complications and remaining medical mysteries. As a child she would experience tingling pain in her head, often accompanied by visual disturbances, nausea and vomiting. Shortly after these Read more…
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