The Major Pain podcast is a collection of interviews from people living with chronic illness and disability. Our goal is to spread awareness, empathy and community around experiences often lived through in isolation. Through sharing these stories important themes have become increasingly apparent, including the dangers of medical gaslighting, the importance of self-advocacy and the fact that none of us are in this alone. You can share your thoughts, your story, or inquire about appearing on the show at

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Podcast and website artwork created by Egg Salad Salad. To inquire about artistic services, email

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Major Pain is the recipient of the September 2023 creator grant from the Stimpunks Foundation! The Stimpunks provide mutual aid and human-centered learning for neurodivergent and disabled people. Learn more at

Major Pain is hosted and produced by Jesse Mercury, a content creator with a long history of chronic undiagnosed illness. In 2023 his lifelong mystery was finally solved, when he was diagnosed with mast cell activation syndrome (MCAS) and small fiber neuropathy. Jesse’s other content can be found on Bandcamp, YouTube, TikTok, and his website